| 摘要 |
<p>The invention relates to 1,3,4,5-tetrasubstituted pyrazol derivatives having the structure corresponding to the general formula I: (I), wherein R1 is selected from phenyl, naphthyl, diphenyl and heteroaryl with 5 or 6 atoms, which is substituted by one or several radicals selected from halogen, C1-C10 alkyl, C1-C6 alkoxy, hydroxyl and C1-C6 haloalkyl; R2 is selected from C1-C6 haloalkyl, R3 is hydrido; R4 is sulphamyl-substituted aryl; and aryl is represented by phenyl, naphthyl, tetrahydronaphthyl, indane, diphenyl or a pharmaceutically acceptable salt thereof as well as to a pharmaceutical composition containing the same.</p> |
