| 摘要 |
Disclosed is a process for preparing a highly concentrated protein composition comprising: a) a first ultrafiltering of a first protein preparation to provide a second protein preparation; b) a diafiltering of the second protein preparation to provide a diafiltered intermediate protein preparation; and c) a second ultrafiltering of the diafiltered intermediate protein preparation to provide a third protein preparation; wherein one or more of the first ultrafiltering, the second ultrafiltering, and the diafiltering are accomplished at about 30°C to about 50°C. |
