| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: present invention relates to a compound of formula I , where X is C; W is N; V is C; R1 is hydrogen, methoxy or halogen; R2 is absent; R3 is methoxy or heteroaryl, each of which can be optionally independently substituted with one substitute, selected from G; where heteroaryl is triazolyl or pyrazolyl; E is hydrogen or its pharmaceutically acceptable mono or bis salt; Y is selected from a group which consists of and R10, R11, R12, R13, R14, R15, R16, R17 each independently represents H or methyl, under the condition that, not more than two of R10-R17 is methyl; R18 is selected from a group which consists of C(O)-phenyl and quinazolinyl; D is cyano; A is pyridinyl; G is (C1-6)alkyl. The invention also relates to methods of producing compounds of formula I. ^ EFFECT: obtaining new compounds with antiviral activity. ^ 15 cl, 23 dwg, 48 tbl, 16 ex |
