发明名称 BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, PRODUCTION AND USE THEREOF
摘要 FIELD: chemistry. ^ SUBSTANCE: present invention relates to a compound of formula: which is N-{2-tert-butyl-1-[(4,4-diflurocyclohexyl)methyl]-1H-benzimidazol-5-yl}ethanesulfonamide and its pharmaceutically acceptable salt, their diastereomers, enantiomers or their mixture. The invention also relates to use of this compound in making a medicinal agent with modulator activity of CB1 receptors; to a pharmaceutical composition based on this compound; to a method of modulating CB1 receptors, based on use of effective quantities of this compound, as well as to a method of producing the compound described above. ^ EFFECT: obtaining a new derivative of benzimidazole with useful biological activity. ^ 8 cl, 1 tbl, 28 ex
申请公布号 RU2374234(C2) 申请公布日期 2009.11.27
申请号 RU20070112501 申请日期 2005.09.22
申请人 ASTRAZENEKA AB 发明人 PAZHE DANIEL';LIU ZIPING;TREMBLEH MAKSIM;UOLPOL KRISTOFER;JANG KHUA
分类号 A61K31/4184;A61P1/00;A61P9/00;A61P25/00;A61P25/16;A61P25/22;A61P25/28;A61P35/00;C07D235/14 主分类号 A61K31/4184
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