发明名称 Therapy of platinum-resistant cancer through HER dimerization inhibition
摘要 Disclosed is a use of a HER2 antibody that inhibits HER dimerization more effectively than Trastuzumab, in the preparation of a medicament for treating a platinum-resistant cancer selected from the group consisting of ovarian cancer, primary peritoneal carcinoma and fallopian tube carcinoma, wherein the medicament further comprises an antimetabolite chemotherapeutic agent, wherein the HER2 antibody binds to Domain II of HER2.
申请公布号 NZ551376(A) 申请公布日期 2009.11.27
申请号 NZ20050551376 申请日期 2005.06.15
申请人 GENENTECH, INC 发明人 KELSEY, STEPHEN M
分类号 A61K31/00;A61K39/395;A61P35/00 主分类号 A61K31/00
代理机构 代理人
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