发明名称 Biphenyl-3-yl acetic acids and derivatives thereof
摘要 The disclosure relates to biphenyl-3-yl carboxylic acids derivatives of formula (I) with the definitions of A, X, R1-R6 given in the specification, and/or a salt or ester thereof. Furthermore the disclosure relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of gamma-secretase activity.
申请公布号 NZ554724(A) 申请公布日期 2009.11.27
申请号 NZ20050554724 申请日期 2005.10.21
申请人 CELLZOME LIMITED 发明人 WILSON, FRANCIS;REID, ALISON;READER, VALERIE;HARRISON, RICHARD JOHN;SUNOSE, MIHIRO;HERNANDEZ-PERNI, REMEDIOS;MAJOR, JEREMY;BOUSSARD, CYRILLE;SMELT, KATHRYN;TAYLOR, JESS;LEFORMAL, ADELINE;CANSFIELD, ANDREW;BURCKHARDT, SVENJA
分类号 C07C59/68;A61K31/192;A61P25/28;C07C59/72;C07C235/34;C07C311/17;C07C317/22;C07D261/08;C07D295/18;C07D295/22;C07D309/06 主分类号 C07C59/68
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