PEPTIDE PHARMACEUTICAL FORMULATIONS

摘要

A pharmaceutical composition for administration to a mammal is disclosed. The composition includes a therapeutically effective amount of a peptide, such as a GLP-1 molecule, a PTH molecule, or a GRF molecule. The composition further includes a buffer including a weak acid having an acid dissociation constant value of greater than about 1x10<-5>, such as acetic acid. The composition also includes an excipient for making the composition generally isotonic, such as D-mannitol.