摘要 |
Provided is a method of identifying a melanoma comprising the step of a. measuring the expression levels in a tissue sample of genes encoding mRNA corresponding to specified sequences of PLAB and L1CAM or PLAB, L1CAM and NTRK3, wherein the gene expression levels above pre-determined cut-off levels are indicative of the presence of a melanoma in the sample, and wherein the pre-determined cut-off levels are at least two-fold over-expression in tissue having metastatic melanoma relative to benign melanocyte or normal tissue.
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