| 发明名称 |
TREATING NIEMANN-PICK DISEASE TYPE C AND RELATED DISORDERS BY ELEVATING INTRACELLULAR CALCIUM |
| 摘要 |
<p>The present invention provides a compound which elevates intracellular calcium for use in the treatment of a disease which has a Niemann-Pick disease type C like cellular phenotype. The invention further provides a compound which reduces sphingosine storage for use in the treatment of Niemann-Pick disease type C.</p> |
| 申请公布号 |
WO2009141627(A1) |
申请公布日期 |
2009.11.26 |
| 申请号 |
WO2009GB01295 |
申请日期 |
2009.05.22 |
| 申请人 |
ISIS INNOVATION LIMITED;PLATT, FRANCES, MARY;LLOYD-EVANS, EMYR |
发明人 |
PLATT, FRANCES, MARY;LLOYD-EVANS, EMYR |
| 分类号 |
A61K31/00;A61K31/12;A61K31/221;A61K31/343;A61K31/352;A61K31/4375;A61K31/4415;A61K31/522;A61K31/593;A61P25/00;A61P25/14 |
主分类号 |
A61K31/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
