发明名称 DOCETAXEL POLYMER DERIVATIVE, METHOD FOR PRODUCING SAME AND USE OF SAME
摘要 <p>Provided is a method for producing a Docetaxel polymer derivative by ester bonding any one or more of the hydroxyl groups of Docetaxel with the aspartic acid side chain carboxyl groups of a block copolymer including polyethylene glycol and polyaspartic acid.  The rate of release of the Docetaxel from the Docetaxel polymer derivative so obtained is regulated by adjusting the proportion of bound Docetaxel on the block copolymer and/or the number of bonds.</p>
申请公布号 WO2009142326(A1) 申请公布日期 2009.11.26
申请号 WO2009JP59633 申请日期 2009.05.20
申请人 NANOCARRIER CO., LTD.;HARADA, MITSUNORI;SAITO, HIROYUKI;KATO, YASUKI 发明人 HARADA, MITSUNORI;SAITO, HIROYUKI;KATO, YASUKI
分类号 C08G69/40;A61K31/337;A61K47/34;A61K47/48;A61P35/00;C08G81/00 主分类号 C08G69/40
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