ANTIVIRAL COMPOSITIONS, METHODS OF MAKING AND USING SUCH COMPOSITIONS, AND SYSTEMS FOR PULMONARY DELIVERY OF SUCH COMPOSITIONS

摘要

A pharmaceutical composition comprises particles comprising an antiviral active, wherein the particles have a mass median aerodynamic diameter from about 1 µm to about 7 µm and a bulk density less than about 1.0 g/cm3. A pharmaceutical composition comprises a powder including an effective amount of antiviral and pharmaceutically acceptable excipient, wherein the powder comprises particles comprising having a mass median aerodynamic diameter from about 1 µm to about 7 µm, and a bulk density less than about 1.0 g/cm3. Also provided are pharmaceutical compositions comprising combinations of two or more antiviral actives. Also provided are unit dosage forms, methods of making and using such compositions, and methods and systems for pulmonary delivery of such compositions