发明名称 GALACTOSE DERIVATIVE, DRUG CARRIER AND MEDICINAL COMPOSITION
摘要 The object of the present invention is to provide a novel and useful galactose derivative, which is a component of a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the drug carrier and a medicine. The present invention relates to a galactose derivative represented by the following general formula (I) a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double-stranded RNA, a double-stranded DNA, an oligo nucleic acid). wherein, R1 represents hydrogen, an alkyl having 1 to 10 carbons which may be substituted or 1-(D)-deoxylactito-1-yl; R2 represents a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms.
申请公布号 US2009292005(A1) 申请公布日期 2009.11.26
申请号 US20070280778 申请日期 2007.02.28
申请人 NIPPON SHINYAKU CO., LTD. 发明人 OHGI TADAAKI;UEDA TOSHIHIRO;SONOKE SATORU
分类号 A61K31/7088;A61K47/30;A61P3/00;A61P25/00;A61P29/00;A61P31/12;A61P35/00;C07H15/04 主分类号 A61K31/7088
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