| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a cell proliferation inhibitor which inhibits the interaction between MDM4 and p53. Ž<P>SOLUTION: The cell proliferation inhibitor is composed of a compound represented by formula I (wherein R1 to R5 are each hydrogen, a halogen, an alkyl group or the like; R6 is carbon, hydrogen or the like; R7 and R8 are each hydrogen, a halogen or the like; R9 and R10 are each an alkyl group, an alkenyl group or the like; X is -C(O)-, -CH(OH)- or -C(S)-; Y is -CH<SB>2</SB>-, -C(O)-, -CH(OH)- or -C(S)-; and Z is carbon, nitrogen, a halogen or sulfur) or its pharmaceutically acceptable salt. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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