发明名称 |
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR |
摘要 |
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on at least one Raf protein kinase. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of Raf protein kinases, including melanoma, colorectal cancer, thyroid cancer, ovarian cancer, cholangiocarcinoma, pain or polycystic kidney disease. |
申请公布号 |
WO2009143024(A2) |
申请公布日期 |
2009.11.26 |
申请号 |
WO2009US44178 |
申请日期 |
2009.05.15 |
申请人 |
PLEXXIKON, INC.;IBRAHIM, PRABHA, N.;SPEVAK, WAYNE;CHO, HANNA;SHI, SONGYUAN |
发明人 |
IBRAHIM, PRABHA, N.;SPEVAK, WAYNE;CHO, HANNA;SHI, SONGYUAN |
分类号 |
C07D487/04;A61K31/519;A61P19/00;A61P29/00;A61P31/12;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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