COMPOSITION AND KIT FOR THE DIAGNOSIS OF TGBM NEPHROPATHY

摘要

PURPOSE: A composition for diagnosing TGBM nephrosis using urine is provided to simply disganose TGBM nephrosis and grasp early diagnosis and process of TGBM nephrosis. CONSTITUTION: A biomarker composition for diagnosing TGBM nephrosis contains protein which highly exists in a patient of TGBM nephrosis as an active ingredient. The protein is Heat shock 70 kDa protein 5(Accession No. IPI:IPI00003362.2), Clusterin(Accession No. IPI:IPI00400826.1), Pyruvate kinase isozymes M1/M2(Accession No. IPI:IPI00479186.5), Guanine nucleotide-binding protein G(s) subunit alpha(Accession No. IPI:IPI00095891.2), CD9 antigen(Accession No. IPI:IPI00215997.5), and Ras-related protein Rab-37(Accession No. IPI:IPI00073180.8). An agent for diagnosing TGBM nephrosis contains an antibody which specifically binds to at least three or more proteins. The antibody is monoclonal antibody.