发明名称 |
PROBE FOR DETECTION OF RIFAMPIN RESISTANCE OF MYCOBACTERIUM LEPRAE AND THE KIT |
摘要 |
<p>PURPOSE: A probe, kit and method for diagnosing Rifampin resistance are provided to quickly diagnose Rifampin resistance of Mycobacterium leprae and effectively treat leprosy patient. CONSTITUTION: A DNA probe for diagnosing Rifampin resistance of Mycobacterium leprae contains one sequence among the sequence number 5 to 16. The probe specifically binds with rpoB gene which relates to the Rifampin resistance of Mycobacterium leprae. A kit for diagnosing Rifampin resistance contains a primer amplifying the Mycobacterium leprae and DNA probe. A method for diagnosing Rifampin resistance comprises: a step of conjugating DNA probe on a solid support; a step of hybridizing PCR product of the amplified Mycobacterium leprae with DNA probe; and a step of detecting the hybridized product.</p> |
申请公布号 |
KR20090121610(A) |
申请公布日期 |
2009.11.26 |
申请号 |
KR20080047590 |
申请日期 |
2008.05.22 |
申请人 |
M&D CO., LTD. |
发明人 |
CHO, SANG NAE;LEE, HYE YOUNG;WANG, HYE YOUNG;BANG, HYE EUN;KIM, YEUN |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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