发明名称 Pyrido[2, 1-A]-isoquinoline derivatives as DPP-IV inhibitors
摘要 The present invention provides compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as indicated in the description, or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
申请公布号 AU2004251830(B8) 申请公布日期 2009.11.26
申请号 AU20040251830 申请日期 2004.06.11
申请人 F. HOFFMANN-LA ROCHE AG 发明人 PATRIZIO MATTEI;MARKUS BOEHRINGER;BERND KUHN;ROBERT NARQUIZIAN
分类号 A61P3/10;A61K31/473;C07D471/04 主分类号 A61P3/10
代理机构 代理人
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