发明名称 |
IL-14alpha RNA inhibitors and antibodies to IL-14alpha for treatment of autoimmune diseases and lymphomas |
摘要 |
Provided are antisense poly-2'-O-(2,4-dinitrophenyl)oligoribonucleotides which are complementary to the IL-14alpha gene and/or transcribed IL-14alpha mRNA. Also provided are monoclonal antibodies reactive with discreet IL-14alpha peptides. The oligoribonucleotides and monoclonal antibodies are useful in inhibiting the growth of lymphocytes.
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申请公布号 |
US7622574(B2) |
申请公布日期 |
2009.11.24 |
申请号 |
US20070977778 |
申请日期 |
2007.10.26 |
申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
AMBRUS, JR. JULIAN L.;SHEN LONG;FORD RICHARD;ZHANG CHONGJIE |
分类号 |
C07H21/04;A61K31/70 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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