发明名称 CROSS-LINKED POLYMERS FOR REMOVING BILE SALTS FROM A PATIENT
摘要 A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly cross-linked polymers characterized by a repeat unit having formula (1) or copolymer thereof, where n is an integer, R1 is H or a C1-C8 alkyl group; M is (a) or -Z-R2; Z is O, NR3, S, or (CH2)m; m = 0-10; R3 is H or a C1-C8 alkyl group; and R2 is (b) or (c) where p = 0-10, and each R4, R5, and R6, independently, is H, a C1-C8 alkyl group, or an aryl group, the polymers being non-toxic and stable once ingested.
申请公布号 CA2192592(C) 申请公布日期 2009.11.24
申请号 CA19952192592 申请日期 1995.05.24
申请人 GELTEX PHARMACEUTICALS, INC. 发明人 MANDEVILLE, W. HARRY, III;HOLMES-FARLEY, STEPHEN RANDALL
分类号 C08F265/04;A61K9/52;A61K9/54;A61K31/74;A61K31/785;A61K31/787;A61K31/795;A61P3/06;C08F8/00;C08F8/02;C08F12/26;C08F16/36;C08F20/34;C08F20/38;C08F20/60;C08F26/02;C08F28/02;C08F220/34;C08F220/60;C08F265/10;C08L25/18;C08L29/12;C08L33/14;C08L33/26;C08L39/00;C08L41/00 主分类号 C08F265/04
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