发明名称 |
Photocleavable fluorescent nucleotides for DNA sequencing on chip constructed by site-specific coupling chemistry |
摘要 |
This invention provides a method for determining the sequence of a DNA or an RNA, wherein (i) about 1000 or fewer copies of the DNA or RNA are bound to a solid substrate via 1,3-dipolar azide-alkyne cycloaddition chemistry and (ii) each copy of the DNA or RNA comprises a self-priming moiety.
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申请公布号 |
US7622279(B2) |
申请公布日期 |
2009.11.24 |
申请号 |
US20050591520 |
申请日期 |
2005.03.03 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
JU JINGYUE |
分类号 |
C12P19/34;C07G3/00;C07H19/04;C07H21/00;C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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