发明名称 |
THERAPEUTIC EFFECTS OF BRYOSTATINS, BRYOLOGS, AND OTHER RELATED SUBSTANCES ON ISCHEMIA/STROKE-INDUCED MEMORY IMPAIRMENT AND BRAIN INJURY |
摘要 |
The invention provides for the use of protein kinase activators or boosters of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) or other neurotrophic factors to treat stroke. Specifically, the present invention provides methods of treating stroke comprising the steps of identi fying a subject having suffered a stroke and administering to said subject an amount of a pharmaceutical composition comprising a protein kinase C (PKC) activator or 4-methylcatechol acetic acid (MCBA) and a pharmaceutically acceptable carrier effective to treat at least one symptom of stroke.
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申请公布号 |
KR20090120480(A) |
申请公布日期 |
2009.11.24 |
申请号 |
KR20097018779 |
申请日期 |
2008.02.11 |
申请人 |
BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE |
发明人 |
SUN MIAO KUN;ALKON DANIEL L. |
分类号 |
A61K31/357;A61K31/047;A61K31/407;A61P25/28 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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