CONJUGATES OF DNA INTERACTING GROUPS WITH STEROID HORMONES FOR USE AS NUCLEIC ACID TRANSFECTION AGENTS

摘要

The present invention relates to novel compounds comprising a steroid hormon e linked to a DNA-interacting molecule that target nucleic acids to the cell nucleus. Further, the invention relates to a metho d for introducing nucleic acids into the nucleus of cells with the help of such compounds. Pharmaceutical preparations containing such compound s and the use of such compounds for gene therapy are also provided.