METHOD OF PRODUCING 3-METHYL-7-[4-(BENZHYDRYL-4-PIPERAZINYL-1) BUTYL]XANTHINE AND SALTS THEREOF WITH ORGANIC OR INORGANIC ACIDS

摘要

FIELD: chemistry. ^ SUBSTANCE: method involves alkylation of 7-potassium salt of 3-methylxanthine with 1,4-dibromobutane, with subsequent reaction of the formed 7-(4-bromobutyl)-3-methylxanthane with 1-benzhydrylpiperazine and neutralisation of the obtained base 7-/4-(4-benzhydrylpiperazinyl-1)butyl/-3-methylxanthane with organic or inorganic acid. ^ EFFECT: obtained compounds have better pharmacotherapeutic properties than current antihistaminic drugs. ^ 2 cl, 1 dwg, 2 ex