| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: method is proposed for producing 1-trimethylsilylpropargyl alcohol through silylation of dipropargyl ester of oxalic acid under action of N-trimethylsilyldiethylamine and zinc chloride in a solvent medium at its boiling point with subsequent hydrolysis with hydrochloric acid, extraction and vacuum distillation. Synthesis of dipropargyl ester of oxalic acid by reacting oxalic acid with propargyl alcohol in a benzol medium at its boiling point and constant dehydration is proposed. ^ EFFECT: design of a simple, safe method of producing 1-trimethylsilylpropargyl alcohol, without use of organometallic synthesis and expensive protective groups, with reduction of cost price of the obtained product by using cheaper and readily available reagents. ^ 2 cl, 2 ex |
