发明名称 |
APPARATUS AND METHOD FOR OPTICALLY SENSING ANALYTE CONCENTRATION IN AN ERYTHROCYTE-CONTAINING FLUID |
摘要 |
A device for determination of analytes has optical material with a deposit on a surface thereof. The deposit includes an analyte-reactive reagent and a particulate material for enhancing reflectance of a light beam emitted through the optical material into the analyte-reactive reagent. The enhanced reflectance provides a return of light through the optical material at a level which is not only analytically useful, but involves sufficient returned light intensity so as to enable markedly improved sensitivity and accuracy in analytical determinations. A suitable particulate material is one of hollow spherical particles. Moreover, the particulate material may be selected for a property such as a neutralizing charge that suppresses the membrane-disruptive effects of certain types of optical materials and hemolytic reagents on blood cells such as erythrocytes. |
申请公布号 |
WO2009139889(A2) |
申请公布日期 |
2009.11.19 |
申请号 |
WO2009US03004 |
申请日期 |
2009.05.13 |
申请人 |
LIGHT POINTE MEDICAL, INC.;NOMURA, HIROSHI |
发明人 |
NOMURA, HIROSHI |
分类号 |
G01N21/77;G01N33/49;G01N33/52 |
主分类号 |
G01N21/77 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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