发明名称 |
QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) |
摘要 |
<p>The invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5, Het1, n, Y and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation.</p> |
申请公布号 |
WO2009139709(A1) |
申请公布日期 |
2009.11.19 |
申请号 |
WO2009SE50526 |
申请日期 |
2009.05.12 |
申请人 |
ASTRAZENECA AB;ARGENTA DISCOVERY LTD.;FORD, RHONAN;MATHER, ANDREW;METE, ANTONIO;MILLICHIP, IAN |
发明人 |
MATHER, ANDREW;METE, ANTONIO;MILLICHIP, IAN |
分类号 |
C07D453/02;A61K31/439;A61P11/06;A61P11/08 |
主分类号 |
C07D453/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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