发明名称 ANTIULCER AGENT
摘要 PROBLEM TO BE SOLVED: To provide an antiulcer agent comprising composite hydrotalcite particles as active ingredients, provided that the composite hydrotalcite particles have at least one chosen from an amino acid, picolinic acid, acetic acid, citric acid, glyceric acid, NO<SB>3</SB><SP>-</SP>, CO<SB>3</SB><SP>2-</SP>and SO<SB>4</SB><SP>2-</SP>between layers of hydrotalcite particles having zinc (Zn) solid-dissolved therein, which are layered double hydroxides. SOLUTION: The composite hydrotalcite particles of formula (1): (Mg<SB>a</SB>Zn<SB>b</SB>)<SB>1-</SB>xAl<SB>x</SB>(OH)<SB>2</SB>(A<SP>n-</SP>)x/n-mH<SB>2</SB>O (wherein A<SP>n-</SP>is at least one chosen from an amino acid, picolinic acid, acetic acid, citric acid, glyceric acid, NO<SB>3</SB><SP>-</SP>, CO<SB>3</SB><SP>2-</SP>and SO<SB>4</SB><SP>2-</SP>; n is 1 or 2; and x, a, b and m are values satisfying the relations: 0.18≤x≤0.40, 0.5≤a<1, 0<b≤0.5, a+b=1 and 0≤m<1), which have a small amount of zinc (Zn) solid-dissolved in the hydrotalcite particles and have at least one chosen from an amino acid, picolinic acid, acetic acid, citric acid, glyceric acid, NO<SB>3</SB><SP>-</SP>, CO<SB>3</SB><SP>2-</SP>and SO<SB>4</SB><SP>2-</SP>between the layers, are used as active ingredients. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2009269862(A) 申请公布日期 2009.11.19
申请号 JP20080122246 申请日期 2008.05.08
申请人 KYOWA CHEM IND CO LTD 发明人 TSUZUKI SHINGO
分类号 A61K33/30;A61K9/16;A61K9/20;A61K33/08;A61K47/18;A61P1/04 主分类号 A61K33/30
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