发明名称 |
Novel nucleic acid base pair |
摘要 |
A novel artificial nucleic acid base pair which is obtained by forming a selective base pair by introducing a group having steric hindrance (preferably a group having steric hindrance and static repulsion and a stacking effect) and can be recognized by a polymerase such as DNA polymerase; a novel artificial gene; and a method of designing nucleic acid bases so as to form a selective base pair with the use of steric hindrance, static repulsion and stacking effect at the base moiety of the nucleic acid. An artificial nucleic acid comprising these bases; a process for producing the same; a codon containing the same; a nucleic acid molecule containing the same; a process for producing a non-natural gene by using the same; a process for producing a novel protein by using the above nucleic acid molecule or non-natural gene, and the like.
|
申请公布号 |
US2009286247(A1) |
申请公布日期 |
2009.11.19 |
申请号 |
US20090459794 |
申请日期 |
2009.07.07 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
HIRAO ICHIRO;ISHIKAWA MASAHIDE;FUJIHARA TSUYOSHI;YOKOYAMA SHIGEYUKI |
分类号 |
C12Q1/68;C07H11/04;C07H19/207;C07H21/00;C07K1/00;C12N1/00;C12N1/21;C12N15/11;C12P19/34;C12P21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|