发明名称 Use of glucosamine by oral and/or parenteral way as active ingredient, to prevent and/or treat cutaneous signs of aging and to maintain and/or restore the biomechanical properties of the skin
摘要 #CMT# #/CMT# Use of glucosamine (I) by oral and/or parenteral way, as an active ingredient to prevent and/or treat cutaneous signs of aging and to maintain and/or restore the biomechanical properties of the skin, is claimed. #CMT#ACTIVITY : #/CMT# Dermatological; Antiinflammatory; Antibacterial. #CMT#MECHANISM OF ACTION : #/CMT# Collagen synthesis activator; Epidermal homeostasis promoter; Matrix metalloproteinase inhibitor. Tests details are described but no results given. #CMT#USE : #/CMT# (I) is useful: to maintain and/or restore stretchiness, tonicity, firmness, flexibility, density and/or elasticity of the skin; to prevent and/or fight against skin disorder induced by chronological aging, hormonal aging, extrinsic aging, preferably photo aging, weight loss, preferably observed during a slimming regime, cellulitis, cutaneous pain or pinching induced by cellulitis; and to prevent and/or treat visual appearances associated with cellulitis, skin disorders induced by menopause, cutaneous signs of aging, disorders of the skin associated with skin atrophy and/or with synthesis of deteriorated collagen and/or an over expression of the matrix metalloproteinase (claimed). #CMT#ADVANTAGE : #/CMT# (I) improves the property of contractile fibroblasts. (I) acts on the cellular metabolism and maintains the biomechanical properties of the skin. #CMT#ORGANIC CHEMISTRY : #/CMT# Preferred Components: (I) is sulfate, potassium chlorosulfate, sodium chlorosulfate and glucosamine hydrochloride. (I) is present in the form of a salt, acetylated form and/or polymeric form. #CMT#ADMINISTRATION : #/CMT# Administration of (I) is oral, parenteral (claimed) and/or topical. Administration of (I) is 50 mg-3 g/day, preferably 250-1500 mg/day.
申请公布号 FR2907335(A1) 申请公布日期 2008.04.25
申请号 FR20060054425 申请日期 2006.10.20
申请人 LABORATOIRES INNEOV 发明人 PICCIRILLI ANTOINE;MANISSIER PATRICIA
分类号 A61K8/60;A61Q19/08 主分类号 A61K8/60
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