PROTEINA DE FUSION QUE COMPRENDE UN ANTIGENO ASOCIADO A TUMOR (PRAME) O UN FRAGMENTO INMUNOGENICO DE EL Y UN DERIVADO DE PROTEINA D; SECUENCIA NUCLEOTIDICA QUE CODIFICA DICHA PROTEINA; VECTOR Y CELULA HUESPED QUE COMPRENDEN LA PROTEINA; VACUNA QUE CO

摘要

The present invention relates to fusion proteins comprising an antigen derived from the so-called tumour rejection antigen PRAME (also known as DAGE) linked to an immunological fusion partner which provides T helper epitopes, such as, for example protein D from Haemophilus influenzae B, fusion partner proteins comprising fragments of protein D, methods for preparing the same and for formulating vaccines and use of the same for treating a range of cancers.