| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: new analogues 1-deamino-8-D-arginylvassopressin, which have the following general formula: Mpa-Tyr-Phe-X-Y-Cys-Pro-D-Arg-Gly-NH2, where Mpa is the radical of 3-mercaptoproprionic acid with the formula: SH-CH2-CH2-COOH; X is the amino group which includes alanine, asparagines, glutamine, isoleucine, leucine and valine, Y is an amino-acid from the group, which includes glutamine, isoleucine, leucine and valine. Analogues 1-deamino-8-D-argenyle vasopressin, which has the following formula: where Mpa is the radical of 3-mercaptoproprionic acid with the formula: SH-CH2-CH2-COOH; X is the amino group which includes alanine, asparagines, glutamine, isoleucine, leucine and valine, Y is an amino-acid from the group, which includes glutamine, isoleucine, leucine and valine. ^ EFFECT: products possess increased effectiveness. ^ 14 cl, 6 dwg, 3 tbl, 8 ex |
