| 摘要 |
PROBLEM TO BE SOLVED: To provide a new muscarine M3 receptor antagonist causing no side effects such as bronchodilatation and thirst even when administered by inhalation for treatment of the respiratory organs. SOLUTION: The hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide is provided. The medicinal composition contains the compound or a derivative thereof in an effective amount. The medicament is useful for the treatment of diseases, disorders and pathologic conditions comprising bronchoconstriction, small airways obstruction, pulmonary emphysema, chronic obstructive pulmonary disease (COPD), adult respiratory distress syndrome (ARDS), chronic/acute bronchitis, asthma, bronchiectasis, etc. COPYRIGHT: (C)2009,JPO&INPIT
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