| 摘要 |
PURPOSE: A pharmaceutical composition of transnasal anticonvulsive is provided to improve bioavailability of insoluble anticonvulsive and solubility. CONSTITUTION: A pharmaceutical composition of transnasal anticonvulsive contains insoluble anticonvulsive, diethylglycol monoethylether and fatty acid ester. The fatty acid ester is caprylocaproyl polyoxyl glyceride, isopropyl palmitate, oleoyl polyoxyl glyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate or polysorbate 20. The insoluble anticonvulsive is diazepam or lorazepam. |
