| 摘要 |
A novel sorangiadenosine compound having antibacterial activity, which is isolated from a Sorangium cellulosum is provided to have inhibition activity against gram-positive bacteria and gram-negative bacteria and treat disease caused by bacterial infection. A novel sesqui-terpene adenoside compound of the general formula I is isolated from a Sorangium cellulosum. In the general formula I, R1-R11 are independently hydrogen, halogen group, nitro group, amine group, hydroxyl group, C1-C5 low alkoxyl group, sulfhydryl group, sulfonyl group, carboxyl group, C1-C5 low alkyl ester group, C1-C20 alkyl group, C2-C20 alkenyl group or C2-C20 alkynyl group. A antibacterial composition for treating disease caused by bacterial infection comprises a sorangiadenosine compound of the general formula I and its pharmaceutically allowable salt. The disease caused by bacteria infection is staphylococcus food poisoning, cellubitis, scull furnace infection meningitis, peritonitis, cystitis, lymphangitis, panaritium, tympanitis, and respiratory disease. |
