发明名称 |
HUMAN GROWTH HORMONE DERIVATIVE LINKED WITH POLYETHYLENEGLYCOL, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME |
摘要 |
PURPOSE: A PEG-human growth hormone complex is provided to minimize biological activation and last activation in a body. CONSTITUTION: A PEG-human growth hormone complex contains a human growth hormone and polyethyleneglycol(PEG) of 20 kDa-50 kDa. The PEG is methoxyPEG aldehyde(Mpeg-ALD). A pharmaceutical composition for treating dwarfism and growth hormone deficiency or diabetic ulcer contains PEG-human growth hormone complex.
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申请公布号 |
KR20090118879(A) |
申请公布日期 |
2009.11.18 |
申请号 |
KR20090042035 |
申请日期 |
2009.05.14 |
申请人 |
SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION |
发明人 |
LEE, KANG CHOON;CHAE, SU YOUNG;SON, SO HEE |
分类号 |
A61K47/48;A61K38/27;A61K47/34;A61P5/02 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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