发明名称 METHOD AND COMPOSITIONS FOR CELLULAR REPROGRAMMING
摘要 The present invention provides methods and compositions useful in treating certain diseases herein termed "Aberrant Programming Diseases", including cancer and AIDS. According to one aspect of the invention, there is provided a method for treating an individual having an Aberrant Programming Disease comprising administering to said individual an effective amount of a composition selected from the group consisting of an expression vector, a double stranded oligodeoxynucleotide, and an antisense oligodeoxynucleotide; said composition capable of regulating expression of a transcriptional regulator, said transcriptional regulator being expressed by the Aberrant Programming cells and further characterized by exhibiting a therapeutically useful change in said cell behavior in the Reprogramming Test. In a separate embodiment new antisense oligodeoxynucleotides are provided.
申请公布号 CA2116327(C) 申请公布日期 2009.11.17
申请号 CA19922116327 申请日期 1992.08.24
申请人 发明人 SMITH, LARRY J.
分类号 C12N15/09;C12Q1/68;A61K31/70;A61K31/7088;A61K31/7125;A61K38/00;A61K48/00;A61P31/18;A61P35/00;C07H21/04;C12N15/113;C12Q1/02 主分类号 C12N15/09
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