发明名称 |
DNA POLYMERASES WITH INCREASED 3-MISMATCH DISCRIMINATION 3- DNA |
摘要 |
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases. |
申请公布号 |
HK1183897(A1) |
申请公布日期 |
2016.06.03 |
申请号 |
HK20130111174 |
申请日期 |
2013.09.30 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
REICHERT, FRED, L.;BAUER, KEITH, A.;MYERS, THOMAS, W.;SCHOENBRUNNER, NANCY, J.;SAN FILIPPO, JOSEPH |
分类号 |
C12N |
主分类号 |
C12N |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|