| 发明名称 |
AGONISTISCHE MONOKLONALE ANTIKÖRPER GEGEN TRKC |
| 摘要 |
The invention concerns agonist anti-trkC monoclonal antoibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy. |
| 申请公布号 |
AT446366(T) |
申请公布日期 |
2009.11.15 |
| 申请号 |
AT20010950429T |
申请日期 |
2001.06.22 |
| 申请人 |
GENENTECH, INC. |
发明人 |
DEVAUX, BRIGITTE;HONGO, JO-ANNE;PRESTA, LEONARD;SHELTON, DAVID |
| 分类号 |
C12N15/09;C12N15/13;A61K39/395;A61K48/00;A61P9/00;A61P25/00;A61P25/02;A61P25/28;C07K16/28;C07K16/32;C12N5/10;C12N15/02;C12N15/63;C12P21/08 |
主分类号 |
C12N15/09 |
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