发明名称 NEW USE OF ARTEMIN WHICH IS MEMBER OF GDNF LIGAND FAMILY
摘要 <P>PROBLEM TO BE SOLVED: To provide a means for preventing death of neurons that is one main cause of various nervous disorders from acute injury to long-term degeneration, and for elongating the life of neurons. Ž<P>SOLUTION: The invention discloses a method of protecting neurons in mammals from injury-induced pathological changes and a method of treating neuronal damage in mammals, by administering artemin or its agonist, which is unexpectedly and completely free of harmful side-effects (particularly hyperalgesia) associated with administration of neurotropic factors (for example NGF) in many cases. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
申请公布号 JP2009263360(A) 申请公布日期 2009.11.12
申请号 JP20090089196 申请日期 2009.04.01
申请人 GENENTECH INC 发明人 SHELTON DAVID L;PHILLIPS HEIDI S
分类号 A61K38/00;A61K45/00;A61K38/18;A61P3/10;A61P25/00;A61P25/02;A61P25/04;A61P25/28;A61P43/00;C07K14/47;C07K14/48;C12N5/08 主分类号 A61K38/00
代理机构 代理人
主权项
地址