发明名称 |
LABEL-FREE MONITORING OF EXCITATION-CONTRACTION COUPLING AND EXCITABLE CELLS USING IMPEDANCE BASED SYSTEMS WITH MILLISECOND TIME RESOLUTION |
摘要 |
Systems and methods for improved monitoring of excitation-contraction coupling and excitable cells are provided, which provide millisecond time resolution. The system is capable of continuously monitoring excitation-contraction coupling in a relatively high-throughput manner. The system includes a device for monitoring cell-substrate impedance, an impedance analyzer capable of impedance measurements at millisecond time resolution, electronic circuitry that can engage the device and selectively connect two or more electrode arrays of the device to the impedance analyzer and a software program that controls the electronic circuitry and records and analyzes data obtained from the impedance analyzer. |
申请公布号 |
CA2723223(A1) |
申请公布日期 |
2009.11.12 |
申请号 |
CA20092723223 |
申请日期 |
2009.05.05 |
申请人 |
ACEA BIOSCIENCES, INC. |
发明人 |
WANG, XIAOBO;ABASSI, YAMA;XI, BIAO;ZHANG, WEN FU;XU, XIAO |
分类号 |
G01N27/02;C12M1/34 |
主分类号 |
G01N27/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|