发明名称 METHOD FOR PRODUCTION OF MONOCLONAL ANTIBODY, HYBRIDOMA AND IMMUNOGEN
摘要 <p><P>PROBLEM TO BE SOLVED: To provide an antibody which recognizes specifically the binding region of glycoproteins. <P>SOLUTION: The immunogen is produced by digesting glycoproteins with protease without performing alkaline hydrolysis. An animal is immunized by the above immunogen, and an antibody-producing cell is collected from the animal. A monoclonal antibody is extracted from the antibody-producing cell or its hybridoma. The obtained antibody is applicable to various uses such as a recognition reagent for the binding region of glycoproteins, a recognition probe of tumor markers or a sugar-chain recognition probe, and has tremendous industrial availableness in various fields such as basic medical science, applied medical science or drug discovery. <P>COPYRIGHT: (C)2010,JPO&INPIT</p>
申请公布号 JP2009263318(A) 申请公布日期 2009.11.12
申请号 JP20080118237 申请日期 2008.04.30
申请人 HOKKAIDO UNIV 发明人 SUGAWARA KAZUYUKI;YAMADA SHUHEI
分类号 C07K16/18;A61K39/395;A61P29/00;A61P31/12;A61P31/22;A61P35/00;A61P35/04;A61P37/06;A61P43/00;C12N5/10;C12P21/06;C12P21/08 主分类号 C07K16/18
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