| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an antimicrobial and radioprotective compounds having activity against a wide spectrum of organisms including bacteria, fungi and protozoa and having protection from radiation damage. <P>SOLUTION: The present invention relates to a method of treatment and/or prophylaxis of a microbial infection, comprising a step of administering an effective amount of a compound of formula (I), (wherein X and Y are each a heteroatom; R<SB>1</SB>to R<SB>5</SB>are each hydrogen or a non-deleterious substituent and R<SB>6</SB>and R<SB>7</SB>are each hydrogen or a non-deleterious substituent), pharmaceutically acceptable salts or derivatives or pro-drugs thereof. The present invention also relates to a method for protecting a subject from radiation damage, a method of cancer radiotherapy, and use as an antimicrobial or radioprotective agent of the compound of formula (I) defined above. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |
