| 摘要 |
<p>Use of a substituted benzene compound (I) or its salt for the preparation of a medicament to prevent or treat memory disorders, is claimed. Use of a substituted benzene compound of formula (I) or its salt for the preparation of a medicament to prevent or treat memory disorders, is claimed. X : O or N; R 1-R 4H, halo, preferably F, Cl, Br or I, OH or 1C or 2C alkoxy; R 5, R 6H, 1-6C alkyl, 1-6C cycloalkyl or 6C aryl whose aromatic nucleus is optionally substituted by halo, hydroxy, 1C or 2C alkoxy, CF 3or NO 2; R 7H, OH, 1-3C alkyl or 1-3C hydroxyalkyl; R 8O or -NR 9R 10; R 9, R 10H, OH, 1-3C alkyl or 1-3C hydroxyalkyl; a, d : 0 or 1; and b, c : simple or double bond. Provided that when: X is O, then d is 0; X is N, then d is 1; R 8is O, then a is 1, b is simple bond and c is double bond; and R 8is -NR 9R 10, then a is 0, b is double bond and c is simple bond. An independent claim is included for a pharmaceutical composition or products comprising (I) and an additional compound. [Image] ACTIVITY : Nootropic; Vulnerary; Cerebroprotective; Neuroprotective; Antiinflammatory; Virucide; Anticonvulsant; Cardiant; Vasotropic; Cardiovascular-Gen; Cytostatic; Antialcoholic; Sedative; Antidote; Hepatotropic; Antithyroid; Antiparkinsonian; Neuroleptic; Tranquilizer; Antidepressant; Metabolic; Hypotensive. MECHANISM OF ACTION : None given.</p> |
