| 发明名称 |
PROCESS FOR PREPARING VORICONAZOLE |
| 摘要 |
<p>Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R, 3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol.</p> |
| 申请公布号 |
EP1828170(A4) |
申请公布日期 |
2009.11.11 |
| 申请号 |
EP20050853716 |
申请日期 |
2005.12.13 |
| 申请人 |
DR. REDDY'S LABORATORIES LTD.;DR. REDDY'S LABORATORIES, INC. |
发明人 |
SUNDARAM, VENKATARAMAN;UPPALA, VENKATA BHASKARA RAO;AKUNDI, SURYA PRABHAKAR;MUVVA, VENKATESWARLU;CHITTA, VIJAYAWARDHAN;DONTHULA, ALEKHYA;KHARKAR, MANOJ RAMESH;DEVARAKONDA, SURYA NARAYANA;PEDDIREDDY, SUBBA REDDY |
| 分类号 |
C07D403/10;C07D249/08 |
主分类号 |
C07D403/10 |
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