发明名称 |
AMINOAMIDES AS OREXIN ANTAGONISTS |
摘要 |
<p>The present invention relates to compounds of formula I wherein Ar1, Ar2, Ar3, n, and R1 to R8 are as defined herein and to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. These compounds are orexin receptor antagonists and may be useful in the treatment of disorders, in which orexin pathways are involved, like sleep disorders.</p> |
申请公布号 |
EP2114867(A1) |
申请公布日期 |
2009.11.11 |
申请号 |
EP20080717082 |
申请日期 |
2008.02.25 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
GOBBI, LUCA;KNUST, HENNER;MALHERBE, PARICHEHR;NETTEKOVEN, MATTHIAS;PINARD, EMMANUEL;ROCHE, OLIVIER;ROGERS-EVANS, MARK |
分类号 |
C07C237/06;A61K31/16;C07D213/36 |
主分类号 |
C07C237/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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