发明名称 |
DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS |
摘要 |
The present invention relates to compounds represented by formula (I), or isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof:
in which each substituent of formula (I) is as defined in the specification. The present invention also relates to preparation methods of compounds represented by formula (I), a pharmaceutical composition comprising compounds represented by formula (I) and usage of compounds represented by formula (I) for treating chronic neurodegenerative diseases such as Alzheimer's disease and other diseases induced by aggregation or deposition of ²-amyloid peptide.
|
申请公布号 |
EP2116526(A1) |
申请公布日期 |
2009.11.11 |
申请号 |
EP20070702276 |
申请日期 |
2007.02.05 |
申请人 |
INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA |
发明人 |
LI, SONG;LIAO, GUOCHAO;XIAO, JUNHAI;NIE, AIHUA;WANG, LILI;ZHONG, WU;ZHENG, ZHIBING |
分类号 |
C07C235/12;A61K31/16;A61K31/4965;A61P25/00;A61P25/28;A61P43/00;C07D235/06;C07D241/04 |
主分类号 |
C07C235/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|