The invention provides a cell co-culture for the selective evaluation of the response of a cell of interest in the co-culture, and methods of using the co-culture. The cell co-culture and the methods are suitable for large-scale/high throughput screening for compounds useful for affecting at least one biological function or event of at least one cell type in the co-culture. The invention further provides kits for using the screening assays.
申请公布号
EP2115456(A2)
申请公布日期
2009.11.11
申请号
EP20080728817
申请日期
2008.02.01
申请人
DANA-FARBER CANCER INSTITUTE, INC.
发明人
MITSIADES, CONSTANTINE, S.;MCMILLIN, DOUGLAS W.;NEGRI, JOSEPH M.;MITSIADES, NICHOLAS;ANDERSON, KENNETH C.