发明名称 |
INTERLEUKIN-18-RECEPTOR PROTEINS |
摘要 |
Disclosed are a receptor protein which recognize a novel cytokine, i.e., interleukin-18, a monoclonal antibody specific to the protein, and uses thereof. The receptor protein is useful as pharmaceutical to treat and prevent autoimmune and allergic disease because it suppresses and regulates excessive immunoreaction. The monoclonal antibody specifically reacts with interleukin-18, exhibiting efficacy in purification, detection and inhibition of interleukin-18.
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申请公布号 |
CA2219963(C) |
申请公布日期 |
2009.11.10 |
申请号 |
CA19972219963 |
申请日期 |
1997.12.23 |
申请人 |
KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO |
发明人 |
TORIGOE, KAKUJI;USHIO, SHIMPEI;KUNIKATA, TOSHIO;KURIMOTO, MASASHI |
分类号 |
C07K14/715;A61K38/00;A61K38/20;C07K16/28;C07K16/46;C12N5/12;G01N33/566 |
主分类号 |
C07K14/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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