发明名称 DUAL-ACTING ANTIHYPERTENSIVE AGENTS.
摘要 The invention is directed to compounds having the formula: (I) wherein: Ar, r, Y, Z, Q, W, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 MX2009011487(A) 申请公布日期 2009.11.10
申请号 MX20090011487 申请日期 2008.04.23
申请人 THERAVANCE, INC. 发明人 ROBERT MURRAY MCKINNELL;SEOK-KI CHOI;PAUL R. FATHEREE;ROLAND GENDRON;PAUL ALLEGRETTI;KEITH JENDZA;DARREN MCMURTRIE;BROOKE OLSON
分类号 C07D213/64;A61K31/4164;A61K31/4178;A61K31/4412;A61P9/00;C07D233/64;C07D233/68;C07D233/70;C07D401/10;C07D401/12;C07D409/06 主分类号 C07D213/64
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