| 发明名称 |
TROPANE DERIVATIVES AS CCR5 MODULATORS |
| 摘要 |
The present invention provides compounds of formula (I) wherein, X, Y, R1, R 2 and R2 are as defined hereinabove. The compounds of the present invention ar e modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
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| 申请公布号 |
CA2481482(C) |
申请公布日期 |
2009.11.10 |
| 申请号 |
CA20032481482 |
申请日期 |
2003.03.31 |
| 申请人 |
PFIZER INC. |
发明人 |
WOOD, ANTHONY;TAYLOR, STEFAN COLIN JOHN;STEPHENSON, PETER THOMAS;BASFORD, PATRICIA ANN |
| 分类号 |
C07D519/00;A61K31/46;A61P1/04;A61P1/16;A61P1/18;A61P3/04;A61P3/10;A61P7/06;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P25/00;A61P25/02;A61P25/28;A61P27/16;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D451/04 |
主分类号 |
C07D519/00 |
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